administered for medicinal reasons, of course, can help alleviate the potential "unpleasantness" you may encounter.
For health reasons, I highly recommend that said "medicinal dose(s)" be accompanied by small amounts of a suitable fruit juice, such as pineapple (and perhaps a bit of coconut milk) to help the medicine go down.
Understand that I am not a doctor, nor have I ever received a medical degree of any kind, but I did once stay in a Holiday Inn.