The only place it gets thin on depth is south of Beaufort SC (virginia area). You'll have no problems with bridges. what isn't 65' will open either on schedule or when you arrive.

If for some reason there's a problem with depth somewhere you'll learn about it as you reach the area. We only had a problem in one spot due to the tides. Since it was around sunset we just found a place to park, dropped the hook and continued the next morning at a higher tide.